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Three days later, mechanical hypersensitivity was measured before an acupuncture treatment was given to the affected hind leg, followed by another measurement to obtain the changes in mechanical sensitivity by acupuncture treatment with or without caffeine administration.
Basal and nitroglycerin-evoked mechanical hypersensitivity was evaluated using manual von Frey hair stimulation of the hindpaw.
Development of significant mechanical hypersensitivity was observed in CCI rats after postoperative day 4 (P < 0.05 vs. sham) and heat hypersensitivity developed after postoperative day 2 (P < 0.05 vs. sham).
Mechanical hypersensitivity was determined as response frequency to 10 presentations of a 0.4g von Frey filament.
For this, mechanical hypersensitivity was evaluated from day 1 to day 15 after an intraplantar injection of CFA in mice.
Mechanical hypersensitivity was tested using von Frey filaments (Stoelting, Kiel, WI, USA) by experimenters who were blinded to group assignment.
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The tests of the developmental time window of mechanical hypersensitivity were evaluated at 2, 4, 8 h, and then at 1, 2, 3, 5, 7, and 10 days after injection of BmK I.
This mechanical hypersensitivity is not modified by oxaliplatin.
Mechanical hypersensitivity is also elicited by downregulation of 4E-BP1 in the spinal cord dorsal horn.
The initial data showed that TRPV1-deficient mice exhibit normal responses to noxious mechanical stimuli and that inflammation-evoked mechanical hypersensitivity is not reduced [ 31].
Thermal hyperalgesia and mechanical hypersensitivity were measured for both groups to determine if the SNL model had Mirror image of Pain (MIP).
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