Measurements were performed in triplicate, and means were taken as mechanical hyperalgesic thresholds.
After allowing the animals to habituate to the device for 30 minutes, measurements were taken in triplicate over a period of approximately half an hour and means were taken as secondary mechanical hyperalgesic thresholds.
First, we examined mechanical hyperalgesic responses registered by a Randall-Selitto apparatus while they reported on mechanical allodynic responses registered manually by von Frey filaments.
mechanical pain threshold.
mechanical detection threshold.
Mechanical withdrawal threshold.
CDT, cold detection threshold; WDT, warm detection threshold; CPT, cold pain threshold; HPT, heat pain threshold; MDT, mechanical detection threshold; MPT, mechanical pain threshold; WUR, wind-up ratio.
± 27.8 168.1 ± 32.5 322.3 ± 93.2 CDT cold detection threshold, WDT warm detection threshold, CPT cold pain threshold, HPT heat pain threshold, MDT mechanical detection threshold, MPT mechanical pain threshold.
CDT: cold detection threshold; WDT: warmth detection threshold; TSL: thermal sensory limen; CPT: cold pain threshold; HPT: heat pain threshold; MDT: mechanical detection threshold; MPT: mechanical pain threshold; MPS: mechanical pain sensitivity; WUR: windup ratio; VDT: vibration detection threshold; PPT: pressure pain threshold.
a Z-scores of lip in BMS patients; b Z-scores of tongue in BMS patients; CDT = cold detection threshold; WDT = warmth detection threshold; CPT = cold pain threshold; HPT = heat pain threshold; MDT = mechanical detection threshold; MPT = mechanical pain threshold.
