Sentence examples for mechanical hyperalgesia induced from inspiring English sources

Mechanical hyperalgesia induced by sumatriptan (1 pg and 10 ng) is dependent on the G-protein αi subunit and protein kinase A (PKA), in IB4-positive and negative nociceptors.

Mechanical hyperalgesia [52] and ongoing neuronal discharge [53, 54] evoked by complete Freund's adjuvant (CFA) and tumour necrosis factor-α (TNFα), and mechanical hyperalgesia induced by low doses of monosodium iodoacetate (MIA) [55] are inhibited by TRPA1 receptor antagonists in rodents.

TRPV4 has recently been considered as essential for chemotherapy-induced neuropathic pain as mechanical hyperalgesia induced by Taxol and Vincristine was strongly reduced in trpv4 −/− mice [30], [66].

Previously we have demonstrated that mechanical hyperalgesia induced agonists of novel estrogen receptor GPR30 strongly correlates with the translocation of PKCε in IB4 neurons [39].

MECM significantly reduced the mechanical hyperalgesia induced by PGE2 either when administered preventively or therapeutically.

The mechanical hyperalgesia induced by tumor cells was dose and time dependent.

A strict correspondence between the areas of flare, and mechanical and heat hyperalgesia induced by intradermal capsaicin injection, suggested that all three phenomena are the consequence of neural factors that operate peripherally [11, 12].

This study was designed to assess the role of calcitonin gene-related peptide (CGRP) and its receptor in the generation and maintenance of secondary mechanical allodynia and hyperalgesia induced by intradermal injection of capsaicin in rats.

In addition, the mechanical and thermal hyperalgesia induced by CCI was significantly alleviated during the 2 7 week period after grafts of IASL/hPPE cells and the analgesic effect could be regulated by doxycycline.

Intrathecal injection of PKM2 siRNA not only attenuated CCI-induced ERK and STAT3 activation, but also attenuated mechanical allodynia and thermal hyperalgesia induced by CCI.

Moreover, inhibition of extracellular L1-CAM binding by intrathecal administration of antibody suppressed the mechanical allodynia and thermal hyperalgesia induced by partial SCNT.