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BC While the likes of Batman and Superman, even Spider-Man, tried to go dark and existential and serious, what Joss Whedon seems to be saying with the Avengers is: "Hey folks, it's a comic book movie!" Why take pains to establish the mechanical functionality of, say, a Batmobile?
Improved biological and mechanical functionality of musculoskeletal tissue-engineered constructs is required for clinical application, which can only be achieved by comprehensive multidisciplinary research.
However, the impairment in the material properties of bone tissue secondary to gamma radiation sterilization is a concern since the mechanical functionality of a bone graft is of primary importance.
These findings demonstrate that IL-1 significantly inhibits the chondrogenic development and maturation of MSC-seeded constructs; however, the overall mechanical functionality of the engineered tissue can be preserved through the use of a 3D woven scaffold designed to recreate the mechanical properties of native articular cartilage.
Although these circumferential fibers are severed by radial meniscal tears, tibial contact stresses do not increase until the tear reaches ∼90% of the meniscus width, suggesting that the severed circumferential fibers still bear load and maintain the mechanical functionality of the meniscus.
Achieving biological and mechanical functionality of the newly formed tissue is paramount for tissue engineered structures.
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However, the process of FBR does not necessarily reduce the proposed mesh function of restoring mechanical functionality in a particular region of the body.
The exquisite mechanical functionality and versatility of the human hand emerges from complex neuro musculo skeletal interactions that are not completely understood.
The investigation provides information that are suitable for the actual comprehension of lower urinary tract mechanical functionality and the optimal design of prosthetic devices.
By day 21, after 7 days of low-dose concentrations of IL-1β, all constructs showed continued mechanical functionality that was not significantly altered by the addition of the cytokine (p > 0.05, Fig. 6a).
There is an urgent need in the field of soft tissue engineering (STE) to develop biomaterials exhibiting a high degree of biological and mechanical functionality as well as modularity so that they can be tailored according to patient-specific requirements.
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