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She also develops new tools to measure and control the mechanical forces generated by living cells.
A polymer MEMS sensor was developed for measuring the mechanical forces generated by single adherent cells.
Now Yu Huang and colleagues show that these molecules sense mechanical forces generated by blood flow and play a role in atherosclerosis pathogenesis.
Cells bind FN via RGD-binding integrins α5β1, αVβ1 and αVβ318,19,20 and can apply mechanical forces generated by their contractile machinery and transferred via transmembrane integrins to FN18,20.
By quantifying and modelling tissue stress and deformation in the mammalian epidermis, we find that this balance is coordinated through local mechanical forces generated by cell division and delamination.
Furthermore, the mechanical forces generated by cells themselves, known as cell traction forces (CTFs), also influence many biological processes such as wound healing, angiogenesis, and metastasis.
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A piston rod serves to couple the mechanical force generated inside the cylinder to the external load.
The mechanical force generated by immediate loading may explain the favorable biologic response of bone and surrounding tissue when the design is biomechanically sound.
To interpret how the mechanical force generated by ATP binding and hydrolysis is propagated in these proteins, a coarse-grained elastic network model is employed.
Thrust is a mechanical force generated by propulsion, as explained by Newton's third law of motion: if a working fluid is accelerated in rear direction, the aircraft is accelerated in the opposite direction.
The mechanical force generated during vortex mixing the mixture and the exothermic heat produced during the hydrolysis of the salt added is responsible for the extraction of the alkaloids from the matrix into the aqueous phase.
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