Sentence examples for mechanical force modulates from inspiring English sources

These studies show how mechanical force modulates integrin-mediated processes and other mechanosensors such as gap junctions, hemichannels, primary cilia, transient receptor potential channels (cell targeting), and intracellular mechanosignaling pathways (molecule targeting).

Mechanical force modulates a wide array of cell physiological processes.

The central paradigm of skeletal mechanobiology is that mechanical forces modulate morphological and structural fitness of the skeletal tissues bone, cartilage, ligament and tendon.

These mechanical forces modulate cell morphology, proliferation, migration, differentiation, and production of bone-related proteins in cells via complex signaling cascades [ 2].

The type of mechanical force can modulate differentiation of connective tissue cells.

Chondrocytes in cartilage tissue are constantly exposed to a variety of different mechanical forces that modulate gene expression and metabolic activity in these cells [ 9].

It has become increasingly clear that many aspects of cell behavior can be modulated by mechanical force including cell proliferation, differentiation, migration, and gene expression.

Furthermore, the resulting biophysical changes to the matrix are not sufficient to modulate the cell ECM mechanical force balance or proliferation of resident fibroblasts.

This finding adds mechanical force to the many strategies by which bacteria modulate the host cell cytoskeleton.

We modulated dermal fibroblast shape and mechanical force by disrupting the actin cytoskeleton with latrunculin-A (Lat-A), which rapidly blocks actin polymerization (Gieni & Hendzel, 2008).

Identification of novel mechanoresponsive proteins such as YAP and TAZ will provide new therapeutic targets to modulate the deleterious effects of increased mechanical force.