Sentence examples for mechanical cues that from inspiring English sources

In sum, we provide a library of reference mechanical cues that can be delivered to cells seeded on tissue engineering scaffolds to guide target tissue phenotypes in a temporally and spatially resolved manner.

The ECM provides tissue-specific molecular and mechanical cues that contribute to the maintenance of cellular homeostasis, promote optimal tissue function and if required, mediate wound healing and tissue repair.

Among these examples, we will describe how emerging investigations point the way toward the use of nanotopographic patterning as a means to probe the stem cell niche and ultimately to guide stem cell fate through mechanical cues that govern processes such as adhesion, proliferation, and differentiation.

Overall our data promote a model whereby vinculin controls the transmission of intracellular and extracellular mechanical cues that are important for the spatiotemporal assembly, disassembly, and reorganization of FAs to coordinate polarized cell motility.

Cell responses to thin films of collagen suggest that at least some of the mechanical cues that cells can respond to in their environment occur at the sub-micron scale.

As well as providing a physical connection to the ECM, integrins transmit chemical and mechanical cues that spatially and temporally regulate cytoskeletal dynamics.

This study demonstrates that the fabricated scaffold is capable of transmitting both mechanical and chemical cues that is native to myocardial tissue and supports efficient growth of the CPCs.

ECs are the primary integrator of the mechanical and chemical cues that guide vascular wall physiology and pathology [16], requiring that any analysis of vascular development have single-cell resolution.

Here, we examined whether hPDC differentiation is regulated by adhesive and mechanical cues comparable to that reported for hBMC differentiation.

Formation of multicellular tissues relies on mechanical (stiffness and adhesion), genetic, and signaling cues that are all highly interwoven.

Compliant ground surfaces, such as sand or soggy grass, perturb locomotion by degrading proprioceptive cues that are acquired via ground contact and by mechanical perturbations due to the compression of material underfoot.