Particles with the aforementioned properties often have a core shell morphology and are composed from solid hydrophobic cores providing necessary mechanical properties and soft, hydrophilic, gel-like shells which swell in water and contain chemical groups suitable for covalent immobilization of biomacromolecules.
The basic requirements for polymeric materials in some areas of biomedical applications are that they are hydrophilic, having good mechanical and thermal properties, soft, and oxygen-permeable.
They combine the high hydration and soft mechanical nature of hydrogel networks, with the electrochemical functionality of conducting components allowing precise control of properties.
This work illustrates that the large and porous PGSU scaffolds, characterised with flexible and soft mechanical properties, as well as long-term stability and adjustable degradation kinetics, have high potential for applications in soft tissue engineering.
We argue that both, the synchronization and the non-equivalence of the mechanical responses in hard and soft devices, have their origin in the dominance of long-range interactions.
Most often, accidental encounters with sharp spines and barbs result in little more than mechanical damage to the skin and soft tissues with minor pain and irritation.
The complex and heterogeneous structure of the enthesis is essential to ensure smooth mechanical stress transfer between bone and soft tissues.
For instance, MPA imaging can assess mechanical and optical properties of soft tissue.
In this study, we developed silk scaffolds with tunable mechanical and degradation properties for soft tissue engineering.
