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Before joining Mindshare, Rachel spent over 15 years at global media agency MEC in senior planning roles.
He joined MEC in 2005 as Managing Director, Global Solutions and has been based in New York since 2007.
Milk yield is partly influenced by the number of mammary epithelial cells (MEC) in the mammary gland.
The objective of this study was to investigate the ability of sonography for diagnosis of mucoepidermoid carcinoma (MEC) in the salivary glands.
That research demonstrated a new configuration for experiments at MEC, in which the shock waves and X-ray pulses go through a material in perpendicular directions rather than in the same direction.
Because of this, many countries now face challenges finding and removing MEC in order to return the land to productivity.
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Bisulfite sequencing has become the most widely used application to detect 5-methylcytosine (5-MeC) in DNA, and provides a reliable way of detecting any methylated cytosine at single-molecule resolution in any sequence context.
However, it may also be formed in a two-step reaction; first the methyl-group of 5-meC in CpG-contexts is oxidised to 5-hmeC, and subsequently this residue is deaminated to yield 5-hmeU (Cannon Carlson et al., 1989).
It is thought to have an important role in correcting mismatches resulting from deamination of C or 5-meC in CpG contexts, which are major sources of G→A transition mutations in man (Brown and Jiricny, 1987; Hardeland et al., 2001).
This protocol detected 5-meC in DNA extracts of three budding yeast laboratory strains.
The recent discovery of DNA dioxygenases acting on 5-meC in DNA introduced another conceptual framework for active demethylation.
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