Recently, we demonstrated high accuracy of optoacoustically measured oxygenation in the superior sagittal sinus (SSS), a large central cerebral vein [ 12].
NIRS measured oxygenation in approximately Brodmann's areas 10 [44].
Although one of the aforementioned studies which have directly measured the oxygenation of vulvar carcinomas [ 13] included measurement of normal tissue, these data were obtained in the mons pubis, not in normal healthy vulvar tissue.
Current methods of measuring tumour oxygenation are either invasive (Eppendorf microelectrode) or require administration of chemical agents (e.g. pimonidazole).
It is standard for measuring blood oxygenation; decrease in PO2 is due to hypoventilation, inspiration of hypoxic gas mixtures or impaired gas exchange.
Ross and colleagues [ 4] examined the ability of injury severity measures, oxygenation, and mental status to predict the need for prolonged ventilatory support in trauma patients.
NIRS measures oxygenation at the microcirculatory level in vessels of diameter <1 mm [92].
Oxygenation was assessed measuring partial pressure of oxygen from peripheral arterial blood samples (PaO2) and calculating the oxygenation index (OI) as (FiO2 × Pawm)/PaO2, where Pawm is mean airway pressure.
In view of growing concerns regarding the optimal supplementation of oxygen at birth, we measured cerebral oxygenation during the first minutes of life.
Therefore, we measure the blood oxygenation of erector spinae muscles of nursing staff while they carrying patients from bed to bath as Figure 13 indicates.
