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However, when measuring multiple parameters it is not practical to move participants constantly between instruments.
Multipurpose phantoms have also been designed in several countries (e.g., the Czech Republic and Poland) for measuring multiple parameters simultaneously [ 8– 14].
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[10054488, Development of cellular metabolic rate analyzer that can simultaneously measure multiple parameters (pH, dissolved oxygen, and metabolic heat) from less than 1000 cells].
A combination of better labeling reagents and better optics creates opportunities to detect and measure multiple parameters at the molecular and cellular level.
It uses cell lines in culture, depends upon the ability to measure multiple parameters after perturbations in a controlled system, and focuses mainly on ErbB-PI3K pathway signaling.
The system measures multiple parameters over several weeks in the home-cage and, with any mutant we have tested so far, can detect even early-onset and/or subtle deficits in motor function.
Methods have ranged from very simple devices consisting of a tape recorder placed in a room with a patient to complex devices capable of measuring multiple physiologic parameters including cough [ 6, 13- 15, 18- 29].
Such a technology should possess the following characteristics: (1) noninvasiveness; (2) label-free; (3) fast-acquisition; (4) high-spatial resolution, and (5) capable of measuring multiple functional parameters, such as hemoglobin oxygen saturation (sO2) and blood flow; however, no existing technology satisfies all the above requirements.
Also highlighted are the merits of low-throughput screens that measure multiple parameters at high accuracy, and of using the desired substrate and reaction conditions rather than surrogates.
By measuring multiple functional, structural and biochemical parameters and their structural/biochemical basis, we have been able to assemble a pathogenic composite for each disease.
Being able to measure multiple plasma parameters at such high time resolutions may provide a key to unraveling some of the cause/effect relationships in auroral forms. 5.
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