Suggestions(1)
Exact(3)
One example of a problem the modeling might solve, says Hood, is measuring multiple biomarkers in order to monitor the effects of disease treatments.
Whereas current serum screening methods require additional sample volume for each additional marker, other immunoassay methods have emerged that allow measuring multiple biomarkers in a constant and relatively small volume of sample material.
Net reclassification improvement (NRI) [ 40] was used to measure the additive value of measuring multiple biomarkers and to quantify improvement in performance over procalcitonin alone, which has previously been shown to be the best biomarker of SBI in Malawian children with signs of severe sepsis [ 29].
Similar(57)
Thus, the cost of testing these biomarkers has been reduced, which makes it feasible to measure multiple biomarkers in primary care or large populations in the future.
We also measured multiple biomarkers of both inflammation and oxidative stress, as different markers may result from different mechanisms and may lead to different downstream health effects.
Protein microarray technology is a rapidly evolving field, driven by the need for high-throughput methodology to measure multiple biomarkers in clinical samples.
The ability to rapidly measure multiple biomarkers, coupled with well-validated data sets, not only means that diagnosis of sepsis can for the first time be moved nearer to the patient but also has high value in subsequent patient management and therefore prognosis.
Unique aspects of this study were that it (1) examined critically ill patients at high risk of developing AKI secondary to significant kidney hypoperfusion; (2) captured patients very soon after insult; and (3) measured multiple biomarkers repeatedly from the earliest practicable time point following insult.
The relatively recent introduction of a multiple reaction monitoring (MRM) mass spectrometry platform for the measurement of peptides has provided the opportunity to develop multiplexed assays for simultaneously measuring multiple candidate biomarkers and to progress them through the biomarker development pipeline [ 65].
There is a need to identify existing data sets or collect and analyze new data that measure multiple biomarkers of Hg in individuals concurrently and repeatedly over the course of a year or longer.
In addition, with the advance of biomarker measurement technology, we can simultaneously assess multiple biomarkers with one blood sample; for example, adiponectin, resistin and PAI-1 were measured simultaneously in our study.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com