Exact(3)
In addition, CD34 immunohistochemical analysis was used for measuring microvessel density (MVD) of the tumor tissues.
Other approaches include measuring microvessel density or circulating endothelial cells.
Three of the 20 articles [ 14, 45, 47] examined potential causes of between-study heterogeneity; for example, Trivella et al. [ 14] perform subgroup analyses according to the method of measuring microvessel density.
Similar(57)
Tumor angiogenesis can be investigated in several ways: (i) by measuring microvessel densities (MVDs) or microvessel areas (MVAs) in tumor tissues, (ii) by quantifying angiogenic molecules or angiogenic receptors within tumor tissues, or (iii) by measuring angiogenic factor levels in serum and urine of cancer patients [ 21- 25].
The activity of tumor's angiogenesis can be assessed by measuring microvessels density in its tissue.
Immunohistochemically measured microvessel density (MVD) has been applied to quantitate the angiogenesis in breast cancer.
Thus, although we did not measure microvessel density in this study, it may be necessary in large scale to elucidate a possible role of VEGFR-3 in lymphangiogenesis.
Immunohistochemistry was used to quantify microvessel density and apoptosis.
Tumour slices were additionally stained with CD-31 antibody to quantify microvessel density (MVD).
The assessment of a tumour's angiogenic potential, by measuring the microvessel density in histological sections, assumes that a 4-microm section is representative of whole tumour vascularity.
That is why it would be useful to measure the microvessel density distribution in all five regions for both 2D and 3D in normal breast tissue obtained from autopsies and prophylactic mastectomies as well as breast reduction surgery.
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