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The accuracy of Lungview® for measuring lung tissue volume was recently assessed by instilling known volumes of water and albumin into a fixed spongy textured human lung phantom [ 15].
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Design/methods: We measured lung tissue concentrations of nicotine and cotinine in SIDS (n = 44) and non-SIDS cases (n = 29) stratified according to household smoking status.
Fourth, mediators were measured in lung tissue, but not in blood.
Multiple mediators of inflammation and injury (ICAM-1, NF-κB, RAGE, PCIII, and E-cadherin) were measured in lung tissue at necropsy, but none were significantly different either within or between groups.
Fibrosis, collagen, collagenases, gelatinases, TGFβ and IL-10 were measured in lung tissue.
IL-6, IL-1β, caspase-3, and PCIII mRNA expressions were measured in lung tissue.
AP-1 and NF-κB binding; total expression and phosphorylated forms of JNK, p38, and ERK1/2; PARP; IHC; and MIP-2 mRNA expression were measured in lung tissue.
NF-κB DNA-binding activity measured in lung tissue homogenates was higher in the VILI group (1.51 ± 0.088 OD) than the sham and LPV groups (0.28 ± 0.056 and 0.17 ± 0.014 OD, respectively) (P < 0.05).
The mRNA levels were measured in lung tissues from healthy donors using different reference samples.
In order to confirm in vitro results, PARP levels were measured in lung tissues of mice bearing tumours.
In our pilot study, we measured neither aerated lung tissue nor FRC and we did not assess markers of lung injury.
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