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The paper sparked great interest in the use of microarrays for measuring gene activity, which helped Dr Shalon attract customers for Synteni, his newly formed company, which offered gene-expression analysis on a service basis.Affymetrix began to sell its first gene-expression arrays in the mid-1990s, moft of which were shipped to pharmaceutical companies and scientific collaborators.
The team's approach for measuring gene activity could be "used as a diagnostic tool for predicting the quality of a transplant".
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To discover why, the scientists measured gene activity in the animals.
The researchers measured gene activity in four different strains of mice with defective rod cells.
By using gene chips to measure gene activity, Svante Pääbo of the Max Planck Institute for Evolutionary Anthropology in Leipzig, Germany, and colleagues have now shown that this may indeed be the case.
They measured gene activity in the venom gland and in the so-called accessory gland, a poorly understood structure through which the venom passes before it leaves the cobra's mouth.
When the researchers measured gene activity, they found that the iPS cells were more similar to the ES cells they descended from than to each other, suggesting that the source of the cells explains many of the disparities researchers had noted between the two stem cell types.
To measure gene activity and patterns of gene expression in the brain, the GEN-SAT team inserts a reporter gene for enhanced green fluorescent protein into each BAC.
However, some of the edges of a causal influence network may be indirect, i.e. mediated by other (measured) gene activities [26].
So, we use it here to measure gene coordinate activity within a functional module.
To measure reporter gene activity cells were washed once with PBS and lysed in 50 µl passive lysis buffer (0.2% Triton X-100, 100 mM K2HPO4/KH2PO4 pH 7.8).
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