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Measuring cognitive changes in this population is challenging.
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Further, in the same way that the CNCEQ has been found to be a sensitive measure of treatment-related reductions in distorted processing (Kolko et al. 2000; Silverman, et al. 1999), it is likely that the CNCEQ-R will be of substantial importance in measuring cognitive change in clinical and research settings.
Curvilinearity refers to the unequal sensitivity of the cognitive test to measure cognitive change.
Despite its intrinsic limitations for measuring subtle change in ability, the MMSE is frequently used to measure cognitive change over time.
OBJECTIVE: The lack of an accepted standard for measuring cognitive change in schizophrenia has been a major obstacle to regulatory approval of cognition-enhancing treatments.
The accepted standard for measuring cognitive change is the ADAS-cog.
Floor effects, in particular, limit its usefulness in measuring cognitive capabilities or changes in cognitive function related to therapy [ 7].
This is supported by a recent study indicating that a certain exposure duration might be needed to measure cognitive performance changes [ 11].
While researchers say further research is needed to evaluate larger numbers of people and measure other cognitive changes, the results do suggest mindfulness-based stress reduction (MSBR) may help protect areas of the brain affected by dementia.
For the study, the researchers examined data on 2,124 healthy women, and gave them regular tests over the course of six and a half years, on average, to measure for cognitive changes.
Stable and sensitive instruments to measure subtle cognitive changes in MCI due to AD as well as in early AD are not yet in place.
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CEO of Professional Science Editing for Scientists @ prosciediting.com