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To the present authors' knowledge, quantitative methodologies for measuring bone quality and its microarchitecture have never been used to study retrieved HR prostheses.
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Currently there is no gold standard method to measure bone quality in the foot.
While difficult to measure, bone quality (alterations in bone geometry and microarchitecture) is also thought to be reduced with aging and contributes to compromised structural integrity of bone.
Local bone quality is determined by measuring bone mineral density and bone mineral content at the contralateral radius.
In addition, we assessed bone quality of the supporting bone directly beneath the implants by measuring bone density and porosity.
The problem is how you measure bone mass.
Because bone stiffness predicts fracture independent of BMD, it is considered to be a measure of bone quality that also accounts for factors related to fracture that might not be detected by a measure of BMD alone.
Additional measures of bone quality, such as microarchitectural characteristics and bone tissue properties, including the presence of damage, may improve the diagnosis of fracture risk.
Although all of these techniques provide measures of bone quality, QCT, pQCT, and BMA are performed only in highly specialized centers and are not recommended for the routine evaluation of postmenopausal osteoporosis (grade A recommendation).
We counted the number of osteoblastic (CD44-positive) cells as a quantitative measure of bone quality.
For clinical investigations into longitudinal changes in HR-pQCT-derived measures of bone quality, it is critical baseline and followup scans be matched, since bone structure and geometry vary substantially along the axial direction [ 16].
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