Differences between nucleotide and haplotype diversity has been measured across different genes such as Sucrose Synthase 3 in rice (Lestari et al. 2011) and OsDREB1F in wild and cultivated rice (Singh et al. 2015a).
The goal of these studies was to determine whether assessment of contractility and hemodynamics, when measured across different laboratories using the same protocol, could consistently detect drug-induced changes in the inotropic state of the heart using drugs known to have clinically relevant positive and negative effects on myocardial contractility.
Ensuring that scales are robust to measure across different age-groups is important to enable outcomes to be monitored longitudinally.
However, previous research has shown that linkage disequilibrium (LD) can also be measured across different chromosomes, and may explain more genetic variation in complex, polygenic phenotypes [ 33, 34].
First, we extracted 1,300 intrinsic genes that could be reliably measured across different microarray platforms for use in human breast tumor profiling [ 12].
As in the analysis of the pre-SWR firing sequences, spike-times of different cells measured across different SWR events were combined within a session to calculate the correlation coefficient.
It is not clear whether abnormalities of cortical anatomy in AD can be reliably measured across different subject samples, how closely they track symptoms, and whether they are detectable prior to symptoms.
When using only the high-variance genes, we gained additional improvement ICC coefficient (median = 0.84, P < 2.2 e − 16), demonstrating that high-variance genes are more reproducibly measured across different microarray platforms.
While all reference barcodes robustly replicated close to the average fitness of 1.0, the attenuating vectors and some kinase mutants showed statistically significant reductions in fitness that were consistently measured across different days of the infection.
Indeed, a strong correspondence between expression variability due to stochastic processes in single cells from the same population and variability of gene expression in a population measured across different conditions is commonly observed.
