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Organochlorine measures were categorized into quartiles because of potential nonlinear associations.
With consultation from the expert panel, measures were categorized into domains and sub-domains of the conceptual framework (Table 1).
Further, outcome measures were categorized into three types: 1) reliable and valid outcome measure, 2) reliable, but not valid outcome measure, and 3) neither reliable, nor valid outcome measure.
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For the customized birth weight percentiles, multinomial logistic regression was used, given that the outcome measure was categorized into three groups: appropriate-for-gestational-age, SGA, and LGA infants.
Body composition measures were categorized as in Table 3 and entered into the model as ordinal.
Continuous lipid values measured at baseline were categorized into quartiles.
Only those studies that measured crystal length were categorized into the growth section.
Any studies that used MSU seed crystals in the assay for measuring crystal weight were categorized into "nucleation" rather than "growth", as these experiments cannot differentiate between newly formed crystals and growth of existing seed crystals.
In our analysis, those studies that reported to measure nucleation or precipitation were categorized into this stage of crystallization.
The measures used for data collection were categorized into sociodemographic characteristics, history of testing, and barriers to testing.
To ensure that the measure considered multi-system impairment, deficits were categorized into five general domains (physiological, psychological, cognitive, social and service use) following guidelines in the literature.
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