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We therefore adopted an approach that did not seek to impose standard concepts or measures (something we felt was neither conceptually nor operationally feasible) but rather to work with the national peculiarities of our three countries.
Tullow was also helped by a positive note from analysts at Oriel: Since we established our thesis on Tullow in September 2014, the company has taken most measures that we felt were necessary in the current environment, including cutting exploration costs and the dividend.
For the efficacy endpoints, we choose only a selected few measures that we felt were clinically significant.
We elected to include a small number of key competence measures as we felt that we could not interpret confidence entirely isolated from competence.
We excluded extreme measures, which we felt were more likely to be attributable to undetected errors in technique than to be truly representative of the child's respiratory health.
We specifically selected eight measures that we felt would be meaningful to patients and were previously evaluated in the VBCSO database; [ 4] we included two additional measures (use of needle biopsy for pre-operative diagnosis, and use of neoadjuvant chemotherapy for T2/T3 tumors) that showed broad variation during data collection.
Given that the TMT and the FTMT are both measuring executive functioning, we felt that a moderate correlation would exist between these two measures.
The petition was a last, desperate measure, Garnett said: "We felt we had to do something after half a year".
Because this dose is measured imperfectly by questionnaires, we felt the measurement error could be large compared with the particle doses we were examining and could obscure any association with our exposure.
Social impact is a notoriously tricky area to measure, and we feel we have only just started to scratch the surface through the findings mentioned above.
Currently we do not measure ourselves like this but we do benchmark utility bills for example and that shows the financial saving but more importantly it is the value in educational terms that we like to measure and we feel this is a real strength.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com