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However, a clear trend toward a better performance of the onabotulinum toxin A-treated patients across all time points and for all considered parameters, including pain perception and disability measures, was detected.
Through random permutations, a significant difference between these two measures was detected within this species.
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With the exception of significantly elevated serum prolactin after escitalopram, no effects in the secondary outcome measures were detected.
These summary measures were detected from spline-fitted changes in body weight over time for each individual animal.
No significant differences in these measures were detected between genotypes (Fig. 5B D) [novel object recognition (NOR): F 2,25)= 0.897, P=0.42; spatial relocation recognition (SRR): F 2,25)=0.779, P=0.47].
Women classified as false positive were assumed to have fewer clinic visits and no diabetes medication costs, because it was considered that treatment would most likely discontinue once normal blood glucose measures were detected.
The trusted measure was detected through the front-end and back-end modules.
The strongest association with the reading measure was detected with the rs8040756 marker (df = 4, β = 18.68, P = 0.026).
An alternative approach to sensitivity analysis could have been used, altering the chosen transition probabilities until a 10% change in the outcome measure was detected.
Furthermore, no association with Larsen score at 1 year or with any other clinical outcome measure was detected (data not shown).
Formation of both 4HNE and Eth were blocked in cultures treated with a peptide inhibitor of NOX2 assembly, gp91ds-Tat., thus confirming that these outcome measures are detecting superoxide in these studies.
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