We demonstrated this by using both EF5 immunohistochemistry and by measuring tissue hemoglobin saturation.
As an alternate method of assessing tumor oxygenation, we measured tissue hemoglobin oxygen saturation (SO2) in a group of mice prior to erlotinib therapy and on day 5 of erlotinib therapy.
The NIRS probe was placed on the thenar eminence to measure tissue hemoglobin oxygen saturation (StO2).
Robles et al. [ 14] investigate the ability to measure tissue hemoglobin concentration and oxygen saturation levels using spectroscopic optical coherence tomography.
DOS signatures are used to measure tissue hemoglobin concentration (total, oxy-, andeoxy-formsms), tissue hemoglobin oxygen saturation (oxy-hemoglobin relative to the total hemoglobin), water content, lipid content and tissue scattering.
In particular, we have developed a portable optical instrument using visible-near-infrared light to evaluate the local microcirculation of periodontal tissues by measuring tissue hemoglobin concentrations and oxygen saturation in a non-invasive and real-time manner [ 13, 16, 17, 23].
For these studies, a prototype clinic-compatible system (v100, Modulated Imaging Inc., Irvine, CA) was used to measure tissue oxygenated hemoglobin, deoxygenated hemoglobin, and tissue oxygen saturation (stO2).
Another noninvasive technique used is near-infrared spectrometry (NIRS) [18, 19], which measures skeletal muscle tissue hemoglobin concentration and oxygen saturation before and after stagnant ischemia.
Another noninvasive technique used is near-infrared spectrometry (NIRS) [ 18, 19], which measures skeletal muscle tissue hemoglobin concentration and oxygen saturation before and after stagnant ischemia.
To test whether the variations of tissue hemoglobin concentration (∆THb) measured by the FORE-SIGHTTM cerebral oximeter can accurately detect changes in arterial hemoglobin concentration (∆AHb) before, during, and after cardiopulmonary bypass.
