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The methodologic advances have included the selection of pre-existing outcome measures that detected change in a sensitive fashion (in rheumatoid arthritis, this was the Core Set Measures).
The two measures that detected group differences in the problem gamblers both involved abstract points reinforcement, and some degree of resemblance to real-life gambling.
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Third, compared to measures that detect linear correlations, nonlinear association measures lose statistical power more quickly with the increase of random additive noise.
It has been challenging to find measures that detect functional changes in people estimated to be relatively far from motor diagnosis.
25 Pearson's correlations investigated the relationship between change measured by each speech and language measure and that detected by the FOCUS.
Indeed, FLO1 de-repression in the absence of both Hda1p and Rpd3p was measured at 21% of that detected in the absence of CYC8.
As expected, HIV-1ΔPTAP, ΔYP was poorly released from control 293T cells, as measured by western blot that detected virion-associated CA and MA proteins, and low viral titers (lower right panel, lane 1).
H NMR spectroscopy is a robust measuring technique that detects small molecules with at least one H-atom.
For individuals with prodromal HD, it has been challenging to find sensitive daily function measures that can detect longitudinal change.
This finding is crucial for the timing of treatment against degenerative conditions such as POAG, as cost-utility analysis should employ valid utility measures that can detect genuine changes in preferences over different stages.
This delay means there is a need for more sensitive measures that can detect the process of bone and cartilage damage, which may therefore be predictive of radiographically assessed progression of joint damage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com