The MA was measured since this measurement takes into account the pixels that are falsely classified.
We focus on a node-specific measure, since this allows us analyzing the restructuring from the perspective of our two case study countries.
Mean fluorescence intensity (MFI) of each sample in the FL1 channel was measured, since this corresponds to R123/BODIPY retention.
In this study Gower distance was taken a distance measure, since this measure can handle a mix of datatypes (binary, discrete and continuous).
VEGF concentrations were measured, since this parameter has been widely studied in human patients affected with Kawasaki Disease (KD), an acute febrile systemic vasculitis of children.
Although hospital mortality was also available, we did not use this outcome measure since this varies widely across centres and countries as a result of different policies for hospital discharge.
In a study focusing on this issue [ 29], 86% of smokers agreed with lung function being measured since this could increase awareness of the negative effects of smoking and increase motivation to give up smoking.
One other potential limitation of our study is the fact that we used the impact factor of scientific journals as outcome measure, since this index is essentially aimed to provide a measure of quality of journals rather than to evaluate the productivity of individual scientists [ 19].
7 Testing bone biochemistry may explain the reason for transaminase not being measured, since this group contained a higher proportion of female patients who are more susceptible to bone disease, such as osteoporosis, and had a higher median ALP, which is a marker for bone disease.
