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The criteria for inclusion of studies included studies with high and reference fluoride exposures, end points of IQ scores or other related cognitive function measures, presentation of a mean outcome measure, and associated measure of variance [95% confidence intervals (CIs) or SEs and numbers of participants].
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A high value speaks in favor of the alternative strategy, to measure presentation times of S+ and S−.
The Structured Positive and Negative Syndrome Scale (SCI-PANSS) [ 33] was used to measure present symptom presentation and severity in this mixed cohort because it measures similar symptom domains in patients with schizophrenia or bipolar disorder [ 34].
Height and weight are measured upon presentation to clinic; these measures were used to calculate the body mass index (BMI) which was then entered into the DEC database.
Figure 4 presents these measures across presentations for correct and incorrect trials separately.
Main outcome measures: Prevalence, presentation, diagnostic modalities, surgical treatment, and relation to intrauterine device (IUD) use.
Proportionate changes in brain measures at presentation were calculated as (measured value at day 5 − measured value at baseline)/value at day 5. Proportionate volume changes were correlated with cognitive variables at 6 months.
Thirty of the outbreaks could also be categorized by setting and had detailed information on the generation that the outbreak was identified, control measures, clinical presentation of the index case, and the number of missed cases (Table 2).
The diversity among studies with regard to patients (type and severity of CP), interventions (type, frequency, duration, and setting), outcome measures (diversity, presentation of the results), and methodological quality of the studies did not allow us to perform a quantitative analysis (meta-analysis).
Extra-pulmonary effects measured at presentation included ECG measurements, serum potassium level and blood sugar level, which were collected from the hospital medical records.
The WHR in this study was measured at presentation in cases and, since most patients presented in an advanced stage of disease, there may have been significant weight loss among the cases prior to recruitment.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com