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The measures of sun protection benefits and sunscreen barriers were taken from Jackson and Aiken [ 21].
Measures of sun sensitivity and exposure were ascertained from computer-assisted personal interviews.
The results are not adjusted for sun exposure because we did not have measures of sun exposure during the intervening period.
The remaining IRF4 SNPs evaluated were not found to be statistically significantly associated with measures of sun sensitivity (data not shown).
We attempted to control for measures of sun exposure by evaluating two variables in our dataset: childhood tan level and childhood skin reaction to two hours of sun exposure.
Table 4 shows associations between the two a priori IRF4 SNPs of interest (rs12203592 and rs12211228) and measures of sun sensitivity and sun exposure among non-Hispanic Caucasian population controls.
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UV spots are a recognized measure of sun damage by dermatologists.
Fitzpatrick skin types are widely used in photobiology as a measure of sun sensitivity.
We extended previous research by also examining an objective measure of sun exposure.
Therefore, we used time spent walking as a measure of sun exposure.
We did not adjust for natural skin or hair colour, or tanning ability in the multivariable model because these innate characteristics were captured when degree of photoaging, a composite measure of sun sensitivity and cumulative sun exposure, was included in the model [ 30].
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