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Additional measures of prostate cancer volume in needle-biopsies better predict disease outcome.
Outcomes were post-intervention effects on recognized surrogate measures of prostate cancer progression [Gleason score; prostate-specific antigen (PSA)] and clinical measures of prostate cancer progression (metastases, recurrence, disease-free survival, or prostate cancer mortality).
The search strategy specified terms for RCTs, prostate cancer, dietary, nutritional, or physical activity interventions, and surrogate or clinical measures of prostate cancer progression or mortality (see Supplemental Data for Medline search strategy, Online Resource 1).
To be eligible, studies had to be RCTs in men with prostate cancer who were randomized to dietary, nutritional, or physical activity interventions, which reported on surrogate or clinical measures of prostate cancer progression or mortality.
GUI weight correlates closely with other measures of prostate tumour growth and its use reduces time delays and minimises tissue identification ambiguities that arise during dissection as a result of the increasingly disturbed prostate tissue architecture over time in the TRAMP mouse.
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His physician, Dr. Bubley, noticed that Mr. De Grandis's PSA levels, a measure of prostate cancer growth, had begun to fall.
Hypermethylation of the GSTP1 promoter, particularly in combination with other genes implicated in tumourigenesis, is proving to be a highly specific and sensitive measure of prostate cancer.
To establish the dose response relationship between intramuscular (IM) testosterone (Sustanon 5000) injections and ventral prostate weight (as a measure of prostate development), prepubertal male WISTAR rats (2 weeks old) were given IM testosterone injections of 500 μg, 2500 μg and 5000 μg while control animals were given IM injections of vehicle (olive oil) only.
Main outcome measures Risk of prostate cancer calculated as odds ratios and 95% confidence intervals by conditional logistic regression analyses.
It is necessary to note that even after crudely separating out asymptomatic screening from total test use, these calculations are likely to be strict measures of breast, prostate and colorectal cancer screening overuse.
Main outcome measure Validity of prostate specific antigen for prediction of subsequent prostate cancer diagnosis by record linkage to cancer registry.
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assessment of prostate
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