Transfected HeLa cells were radioactively pulse-labeled to follow maturation of full-length CFTR over time by using the acquisition of complex glycans in the Golgi apparatus as a measure of maturation.
However, as an alternative measure of maturation, we found that the lateral dendrites exhibited growth cone-like structures at their tips at P3, 5, and 7 (Figs. 1D, D', and D″).
However, the variable quality of supernumerary human embryos and the lack of functional measures of blastocyst maturation make this research problematic.
The primary health outcomes of interest are thyroid hormone function and measures of neurobehavioral maturation that pertain to school performance and community adjustment.
A cohort of uniform age with measures from early childhood, in addition to measures of pubertal maturation, is needed to establish when IR begins to rise in relation to puberty.
We investigated whether gut development was affected in mutants by measuring indices of maturation, such as villous size and number as well as muscle cross sectional area.
We also determined dual co-localization of bacteria with LC3 and LAMP1 (Figure 5D), as a measure of the maturation of bacteria-containing LC3 phagosomes by fusion with lysosomes.
The number of molecules of Z is taken to be a measure of PG maturation in the model.
Chromatin decondensation of Snrpn Ube3a preceded increased MBII-85 nuclear accumulation concentrated within neuronal nucleoli (Fig. 2C) and correlated with increased nucleolar and nuclear area, a measure of neuronal maturation (Fig. 2D and Supplementary Material, Fig. S4).
