Correlations between copeptin and measures of kidney function, urine volume, sodium, osmolality, and albumin were analysed using the Spearman's rank correlation coefficient (r) for non-normally distributed data.
Furthermore, a multiple testing analysis was not applied to genotypic differences in relation to various measures of kidney function.
Study objectives are to investigate whether NAC affects serum creatinine level independently of alterations in other measures of kidney function.
Also, the high levels of serum BUN and creatinine, routine measures of kidney function, observed after sepsis were alleviated in H1R−/−/H2R−/− mice (Fig. 8d).
Limitations of the study include small size of the sample, small number of C/C genotype patients, and a lack of multiple testing analysis of genotypic differences in various measures of kidney function.
Kidney function is often compromised in frailty and is a key consideration in medication choice and dosing; however, creatinine-based measures of kidney function may be biased in frail individuals.
In addition to the above, blood samples are usually taken to measure urea and creatinine (measures of kidney function, which may be impaired in DKA as a result of dehydration) and electrolytes.
Measures of kidney outcomes.
Methods for quantifying measures of kidney damage and kidney function have been described elsewhere [ 25].
Our design also prohibited the use of more sophisticated measures of kidney function.
