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In the meantime current clinical trials such as the DEFINE-FLOW study which is using invasive measures of fractional and coronary flow reserve will help to define the potential clinical role of non-invasive PET MFR to complement invasive FFR measurements of the physiologic consequences of coronary atherosclerosis [37].
Other studies have shown thalamus abnormalities with measures of fractional anisotropy [47] and glucose metabolism [48] in patients diagnosed with NPSLE and SLE respectively.
Measures of fractional anisotropy (FA) are considered to be overall measures of axonal integrity, reflecting either increased axonal caliber, increased myelin thickness, increased fiber coherence in a given direction, or some combination of these factors [11].
Tract-specific diffusion measures of fractional anisotropy, mean diffusivity, axial and radial diffusivity will be calculated.
IVGTT results were analyzed using the MINMOD program (11) to obtain measures of fractional glucose disappearance due to an increase in insulin above basal (insulin sensitivity [ SI]).
Diffusion tensor imaging measures of fractional anisotropy and diffusivity and arterial spin labeling perfusion imaging obtained in a subset of these participants will also be added to the correlative modeling.
Similar(52)
Cyclic voltammetry and differential capacitance were used to monitor the successive removal of AET from the metal with potential cycling; however, capacitance was determined to be a more sensitive measure of fractional coverage.
By tracking the diffusion of water in the brain a measure of fractional anisotropy (FA) can be derived.
The fractional position of the L31W transition state at 322 K (calculated from the ratio Δ Cp ‡- D /Δ Cp N- D) [26]) is also a measure of fractional ΔSASA upon formation of the transition state analogous to β T [17].
In order to do so, we used measures of mean fractional DNA methylation level and average normalized ChIP enrichment for each coding sequence (CDS) to perform linear regressions and Spearman's rank correlations between epigenetic marks with the JMP statistical software package (SAS Institute Inc).
Secondary objectives were as follows: (1) to measure levels of exhaled prostaglandin (PG) E2, since impaired PGE2 production has been implicated in the pathogenesis of asthma in adults; and (2) to measure levels of fractional exhaled nitric oxide (FeNO), which is a marker of airway inflammation.
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