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We used negative binomial regression models with generalized estimating equations (GEE) (Zeger and Liang 1986) to model the relationship between 3-day average PM and three repeated measures of days of symptoms or rescue medication use during the previous 2 weeks.
Aspects such as the impact of CTS on functioning and health-related quality of life was included in only a few trials and limited to measures of days taken to return to work.
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The primary outcome was assessed by a common cold diary, yielding a subjective measure of days with the common cold.
The present study also utilized composite measures of "unhealthy days" and "healthy days" developed by CDC.
Main outcome measure Number of days with frequent cough after the randomisation visit.
The following sensitivity analyses are planned: 1. Evaluation of the primary outcome measure (number of days off work) by robust Poisson and zero-inflated models.
Our ranking system explicitly avoids such assumptions and instead focuses on measures of present-day accumulated environmental degradation.
CDC's measure of healthy days, a positive complementary form of unhealthy days, was computed by subtracting the number of unhealthy days from 30 [ 15, 23].
In addition, a continuous measure of headache days per month was retained to model variation in headache days within- and between-persons.
Whilst the measure of same-day and next-day provides a proxy for speed of scanning, the specificity and sensitivity of these measures remain uncertain.
The character is based on Dr. Jerome Groopman, a Boston physician who chronicled his clinical experiences in the 1997 book "The Measure of Our Days".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com