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Comparable results were obtained with subsets of as few as 69 of the markers ranking higher for different measures of ancestry informativeness (Text S2).
Allele counts, exact tests for HWE departures [44], and relevant measures of ancestry informativeness of EuroAIMs were calculated using the SNPInfostats software (available from the corresponding author upon request).
Similar results were observed using subsets of as few as 23 of the markers ranking higher for different measures of ancestry informativeness, albeit at the cost of as much as 11% of individuals being classified in the incorrect population (see Text S2 for further details).
Adjusting for STRUCTURE estimates, based on the full marker set or any of the subsets of markers ranking higher for different measures of ancestry informativeness, barely decreased the number of significant tests (Table 3), while significance levels dropped considerably (Figure S2).
Using data published by Behar, he calculated seven measures of ancestry, relatedness, and geographical origin.
However, marker-based relationships may be imprecise measures of ancestry when they are based on the lowest marker densities, which may explain the poor performance of IBS-GS in these scenarios.
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Self identified ancestry was shown in previous studies to be a reliable measure of ancestry [ 21].
Nonetheless, measures of exclusive ancestry over all loci (gsiT) were significant for all lineages except E. cinereiceps (Table 2).
This finding was robust in the SP data set that included genetic risk factors for BMI/obesity as well as measures of genetic ancestry.
Additionally, the measures of genetic ancestry were included to adjust our analyses for potential genetic (as opposed to racial/ethnic) differences on the genome-wide scale.
Finally, on a subset of the overall sample, we utilize genome-wide association data to incorporate a genetic risk score (GRS) for BMI as well as measures of genetic ancestry.
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measures of strain
measures of offspring
measures of progeny
estimates of ancestry
assessment of ancestry
measures of delinquency
measures of well-being
measures of misery
measures of boredom
measures of privacy
measures of worklessness
measures of revenue
measures of Expatriation
measures of knowledge
measures of democratisation
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