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At the same time there is an emerging consensus that the development and use of performance measures can be problematic.
Occupational social class measures can be problematic in postretirement age groups, although our results are consistent with previous studies showing the social gradient in health and disability.
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Finally, a drift in diagnostic tests for measuring outcome can be problematic, particularly in cohort studies.
Waist measures, though practical, can be problematic as many children are "ticklish" and therefore move whilst the measure is being taken or hold their breath/expand their stomach and are unable to "breathe normally" as required for the optimum measurement.
Second, measuring intracellular zinc can be problematic.
Also, while one item measures of theoretical constructs can be problematic to establishing psychometric validity and reliability, the use of scales was not feasible given respondent burden and time constraints for conducting interviews.
Measuring trust through surveys can be problematic.
In Figure 1B where pre-mRNA was measured with intronic primers and signal from contaminating genomic DNA can be problematic, samples measured by quantitative RT-PCR were treated with DNase I (Sigma) per the manufacturer's instructions.
However measuring income and consumption expenditure can be problematic.
Despite increasing interest in evaluating the impact of dyspepsia symptoms on patients' daily lives, measuring this impact in clinical trials can be problematic due to a paucity of validated instruments [ 23].
Unfortunately, these measures are not defined by standard accounting rules, and so they can be problematic to compare across firms.
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CEO of Professional Science Editing for Scientists @ prosciediting.com