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In the second animal model we used repeated measurements (if available) from the same individual, henceforth called repeated measures animal model, and this included fixed effects (instead of corrected values).
All data from the repeated measures animal model are reported in Table S1.
Furthermore, the repeated measures animal model gave lower sampling errors for all traits, with an average improved accuracy of 33%%.
Six of eight morphological traits that were estimated by repeated measures animal model showed significant additive variance (Table S1).
First, the phenotypic variance (VP) was larger for the repeated measures animal model as compared with individual means.
Alternatively, the repeated measures animal model is more powerful in correcting for obscuring effects on the estimation of additive variance.
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Bellomo, R. et al. Acute renal failure - definition, outcome measures, animal models, fluid therapy and information technology needs: the Second International Consensus Conference of the Acute Dialysis Quality Initiative (ADQI Groupp.
Apparently repeated measures animal models offer less biased estimates of rA, but does not manage to reduce the sampling error.
Another reason for the lower h2 from repeated measures animal models compared to parent-offspring regressions is the former's lower additive variance (VA).
Our results suggest that the increased accuracy of heritability estimates when using animal model is mostly due to the inclusion of repeated measures, and that the heritability estimates appear to be lower when using repeated measures animal models.
The purpose of this suite of studies was to investigate the effects of SMT on pain measures using animal models.
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CEO of Professional Science Editing for Scientists @ prosciediting.com