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However, several limitations do not allow to draw any definitive conclusion; among these we underline the small sample size of clinical trials, the variable definitions of CLZ resistance, the heterogeneity of outcome measures and methodological designs.
Evaluating effectiveness of physiotherapy treatment has been impeded by lack of enough quality studies, lack of standardization, a large variety in outcome measures and methodological flaws [ 25].
Both clinical diversity in interventions, patient characteristics or choice of outcome measures, and methodological diversity such as implementation of allocation concealment or blinding can lead to statistical heterogeneity.
Data were pooled using a random effects model as we considered the treatment effects for the individual studies would vary due to expected variability in moxibustion interventions, control procedures, outcome measures, and methodological quality.
Thus, we used levels of evidence as recommended by the Back Group (van Tulder et al. 2003) to do a qualitative analysis regarding the effectiveness of treatment, taking into account the participants, interventions, controls, outcome measures, and methodological quality of the original studies.
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The quality of the evidence base for CBEs is low, as a result of small single sited studies, the use of varied outcome measures, and flawed methodological techniques.
The interpretation of group differences is only based on clinical measures and this methodological choice represents the main limitation of this research.
These indicators have come to be known as 'outcomes' and measuring these outcomes, by means of validated instruments and questionnaires, is now an important field of academic activity that generates a plethora of health-related outcome measures and associated methodological debate.
These inconsistent findings may be due to the use of different measures of exposure and methodological weaknesses including self-reported measure of exposure, small samples (N=94 665) and selection or recall bias (refer to web appendix: Supplementary Table A1).
Some possible explanations for the discrepancies between these findings can be expressed: differing patients' characteristics, heterogeneous insight or QoL measures, sample size and methodological differences.
Each set out to identify views about potential use of the measure and associated methodological issues and to gather feedback on how the ASCOT domains and definitions might be adapted to work at a whole home level.
Related(19)
interventions and methodological
estimates and methodological
precautions and methodological
assessment and methodological
measures and psychological
measures and statistical-oriented
measures and stringent
measures and consistent
measures and qualitative
measures and preventative
measures and positive
measures and mobile
measures and clinical
measures and multivariate
measures and monetary
methods and methodological
measures and methodology
measures and methods
measures and methodologies
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