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We conducted a randomization test to quantify a signal-to-noise ratio in our measurements of sequence homology.
Our measurements of sequence space coverage and entropy allow for the comparison between genomes and between chromosomes within a genome.
Taken together, the measurements of sequence diversity reported here as well as previous observations and theoretical arguments [ 5, 6, 11, 12, 17] suggest that the fate of duplicated genes depends greatly on their functional utility.
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It is important to note that the results of this analysis are predictions only and not direct measurements of sequences that correspond to pathway member or enzyme genes.
Expanding the number of synthetic reporters could provide parallel measurements for the activities of dozens of transcription factors in response to various stimuli, as has been shown with pooled measurements of sequencing and luciferase-based reporters [ 27, 31].
To identify both discontiguously and contiguously conserved regions, we proposed a new measurement of sequence conservation, which measures sequence similarity based only on the conserved segments within the regions.
We have proposed a new measurement of sequence conservation.
We proposed a new measurement of sequence conservation.
Our new measurement of sequence conservation calculates the sequence similarity based on conserved segments.
To identify both types of conserved non-coding regions, we proposed a new measurement of sequence conservation.
The new measurement of sequence conservation proposed in this paper will significantly affect how people study evolution.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com