Blood samples were collected (at −1, 2, 3, 4.5, 6, 7.5, and 9 h from ischaemia (t = 0), and beyond when necessary) and processed for measurement of liver function tests, blood gases and routine haematology (Pathcare Chemical Pathology Service, Cape Town, South Africa).
In addition, fasting plasma samples from these mice were used for measurement of liver function tests and total plasma FFAs.
At the time of sacrifice, blood was obtained from the aorta for measurement of liver functions, and the samples were stored at −20°C.
Biochemical measurement of liver functions revealed that, CCl4 induced a significant increase in plasma AST, ALT, and ALP activity compared with control values, respectively (Table 2).
The usefulness of adding serum PON1 measurement to the biochemical panel of liver function tests was analyzed by multiple logistic regression analysis.
Different from theirs, we focus more on important functional measurements such as the return of bowel function, the recovery of liver function, and the duration of hospitalization.
Serial serum lactate measurements were evaluated, and compared with the biochemical profile of liver function parameters.
It is widely used for the measurement of gastric emptying rate in breath testing or as a surrogate marker of liver function [18 20].
At baseline, 12 and 24 weeks, a fasting blood sample will be taken for measurement of plasma HbA1c, lipids, CRP, liver enzymes (ALT, ALP, AST), FibroTest, and biochemical markers of liver function (creatinine, electrolytes, albumin, bilirubin).
Liver cell transplantation and bioartificial liver may provide metabolic support of liver function temporary and are prospective treatments for patients with liver failure.
