We have shown that the local measurements and inclusion of more mass sensitive observables in the classification processes can improve the classifying quality and also we have shown that muons and electrons energy density can be considered as primary mass sensitive observables in primary mass classification.
Telomere measurements and inclusion criteria for all three datasets have been described elsewhere (Higgins et al., 1996; Andrew et al., 2001; Rietzschel et al., 2007; Kimura et al., 2008).
The primary advantages of the non-equivalent groups design over past research are the pre-post measurement and inclusion of comparison groups [ 13, 14].
The findings with adjustment for potential confounding factors measured at individual and ecological levels are, in general, robust to different periods of exposure measurement and inclusion and exclusion criteria.
These can be addressed partly through careful patient selection, the use of head restraint, and the measurement and inclusion of confound effects into the fMRI analysis; a review of the development of fMRI for the study of epileptic seizures can be found in the study by Chaudhary et al.[ 38 ▪].
In addition, one should bear in mind that on-site measurements and therewith inclusion through care centres (specialized day-care centres and residential facilities) and specialized schools can jeopardise timely inclusion due to potential lengthy procedures.
Multimorbidity, defined as 3+, requires more measurement conformity and inclusion of all chronic conditions, but provides greater specificity than the 2+ definition.
Uniformity of research approaches for PRO development could lead to consistency in health measurement and the inclusion of mixed methods as well as the more sophisticated psychometric methods, such as RMT in accepted international guidelines.
Potential weaknesses of this report are reliance on cross-sectional data, a single measurement of albuminuria, and inclusion of only subjects with diabetes.
The findings will also be important for the design of a subsequent randomized controlled trial (e.g. appropriateness of outcomes and measurements, inclusion criteria for participating nursing homes) and the development of a successful implementation strategy.
However, the previous studies were limited by factors related to study design including variable definition of hypothyroidism, incomplete panel of thyroid function tests (TFTs) or lack of measurements for all patients and inclusion of patients with underlying thyroid disorders.
