The predicate of the development of the CDI was that a focus on locations that have increased susceptibility to cartilage loss would shorten measurement time and increase sensitivity to change [ 16, 34], a notion that our results appear to corroborate.
A shorter measurement time can increase the number of items that a nuclear safeguards inspector can reliably measure during a period of access to a nuclear facility.
Since the measurement time and cost increase proportionally as the increase of measurement points, it is essential to sample measurement points which can represent entire blade with sufficient confidence and accuracy.
In contrast to random errors with a constant variance, the Fisher information can decrease for unknown systematic errors and, thus, the Cramér-Rao bound can increase with an increasing measurement time.
This drift increased significantly with increasing measurement time, thus preventing accurate measurements of long-term pHe changes in the tumours.
This requires either significantly increased costs from denser sensor deployment in the case of global simultaneous/parallel measurements, or increased measurement time and labor in the case of global sequential measurements.
For specific applications the use of (additional) high resolution H NMR spectra could further enhance sensitivity as well as accuracy [ 31], but thereby increase measurement time.
Although it is possible to use off-line high-performance liquid chromatography (HPLC) separation before MALDI-MS measurement, this solution has some disadvantages, mainly the significantly increased measurement time needed to analyse a sample.
When the change in IOP observed during the second crossover period was analyzed by visit and measurement time, mean IOP significantly increased from months 3 to 5 in all but the dorz/brim/tim group at 10 am; from months 5 to 6, there was a statistically significant decrease in IOP in the bim/tim-treated group at both 8 and 10 AM (Table 4).
A further explanation in favour of shorter acquisition times may be that the risk of slight motion artefacts increases with measurement time, perhaps not only in noncompliant patients [ 13].
