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The telomere measurement software package from MetaSystems was used to quantify telomere length on the p and q arms of each chromosome relative to the reference signal on chromosome 2. Our measurements were reported as arbitrary units of Relative Telomere Length Units (RTLU), which is the ratio of telomere signal intensity to the centromere 2 reference signal.
ii) Composite health scores derived using item response theory (IRT) parameter estimates in Winsteps®, a Rasch measurement software package.
Health status scores were computed by using Item Response Theory (IRT) parameter estimates in Winsteps®, a Rasch measurement software package (http://www.winsteps.com).
This general health score was derived using item response theory (IRT) parameter estimates in Winsteps, a Rasch measurement software package (http://www.winsteps.com).
Health status scores were computed using Item Response Theory (IRT) parameter estimates in Winsteps®, a Rasch measurement software package (http://www.winsteps.com).
An overall health status score (HSS) for each respondent was derived from responses to these various items using Item Response Theory IRTT) parameter estimates in Winsteps, a Rasch measurement software package (http://www.winsteps.com).
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Once again we thank Dr. Sabour for his contribution to the important discussion around SUV measurements across software packages.
Differences in SUV measurements between software packages may be due to different post-processing algorithms applied by different vendors to their images before SUV computation [15].
An overall statistically significant difference in SUV measurements between software packages was found in 79% of cases when each pair of variables was compared (p < 0.05).
Repeatability of the measurements is also assessed along the entire workflow: CT acquisition, reconstruction and porosity measurement using commercial software packages.
Although differences regarding techniques and measurements exist among software packages when PET-CT data sets are analysed, this study highlights the importance of standardising all aspects of methodological approaches to ensure accuracy and reproducibility.
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Justyna Jupowicz-Kozak
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