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Unfortunately, measurement of exercise capacity has not been implemented in most clinical practice settings relevant to COPD patients.
Despite the objective measurement of exercise time and intensity, there are challenges related to compliance, data reduction and interpretation in long-term continuous measurements [ 15].
Despite being less often used, cardiopulmonary exercise testing should also be considered as the gold standard measurement of exercise capacity in patients with PAH [ 30].
We will perform a baseline assessment including detailed patient history, questionnaires, lung function, history of exacerbations, measurement of exercise capacity and blood sampling.
Subjective metrics of exercise behaviour, for example, metabolic equivalents derived from questionnaires (Ainsworth et al, 2011 ), are often used in these reports and we agree that objective measurement of exercise behaviour are preferable in clinical trials.
Similar(55)
For example, measurement of exercise-induced cortisol often presents a conundrum based on its equivocal physiological role.
The subjects wore the prescribed garments throughout the whole recovery period (4 h after Ex1 and approximately 18 h after Ex2), except during two repeated bouts of exercise (60 min for each exercise), during measurements of exercise performances, blood drawing, and showering at night.
However, for measurements of exercise induced metabolic rate the flow rate was increased to 1400 mL.min−1.
However, there was no improvement in objective measurements of exercise function after NMES intervention (Table 2).
The questions about exercise are not validated, it would have been ideal to validate the questions with objective measurements of exercise.
Measurements of exercise capacity, physical activity, symptoms and quality of life will be taken at baseline, immediately following the intervention and at 12 months, by a blinded assessor.
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