Measurement of circulating ADM is complicated by a rapid degradation and clearance from the circulation, and is further masked by a binding protein (complement factor H), preventing its detection by standard immunoassay.
It therefore remains unclear which measurement of circulating VEGF actually represents the true amount of biologically active VEGF in the circulation.
Lacroix, R. et al. Impact of pre-analytical parameters on the measurement of circulating microparticles: towards standardization of protocol.
A particular application of the new system is the measurement of circulating single ions.
Mullier, F., Bailly, N., Chatelain, C., Chatelain, B. & Dogne, J. M. Pre-analytical issues in the measurement of circulating microparticles: current recommendations and pending questions.
Measurement of circulating levels of cathepsin K may be useful to assay the number or function of osteoclasts.
Measurement of circulating or in situ cytokine levels provides evidence for a balance between "Th1/Th2" or "Th17/Treg" cytokines in the development of SSc.
The rings could be further optimized for use in accurate label-free identification and measurement of circulating tumor cells in cancer research and disease management.
Background: Minimally invasive radioguided parathyroidectomy (MIRP) combines technetium sestamibi scan, intraoperative gamma probe, methylene blue dye, and measurement of circulating parathyroid hormone (PTH) levels.
Measurement of circulating miRNAs as biomarkers is associated with some special challenges, including those related to pre-analytic variation and data normalization.
It seems that the measurement of circulating levels of inflammatory molecules can be useful in risk assessment or even in the design of therapeutic approaches against the development and progression of coronary atherosclerosis.
