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The attempts to control measurement error were not all equally successful, and even small amounts of measurement error still caused differences in the GWAS.
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Nonetheless, measurement error could still be a source of bias.
However, the measurement error can still be assumed to be included in the multilevel model specification (i.e., the second term on the right-hand side).
– the potential for measurement error is still likely to be lower than the "six months ago" concurrency indicator.
Note that the measurement error model is still distance-dependent based on (4), and is treated as a known value.
The topic of how to assess the unknown parameters with variable measurement error online is still an open to research.
Finally, although our method of assessment, protocol for calibrating HbA1c levels, and guidelines of reporting ensures high accuracy, HbA1c measurement error might be still a concern especially because this index was not derived from repeated measurements over time.
Even if one were to adequately address issues of exposure measurement error, there could still be other methodological issues that could affect the interpretation of an exposure-response analysis.
However, measurement error in THM level estimates may still be present.
Measuring test measurement error: A general approach.
Very small inaccuracies (≈ 0.0001percentt measurement error; Figure 1) can thus still lead to growth rate loss with evolutionary consequences.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com