Furthermore, we have discussed several important limitations such as study design, exposure measurement, and developmental assessment from current literature, which should be interpreted with caution.
We have reported that PTHM profiles differ by sex, brain region and time point of measurement following developmental exposures to Pb ± PS, resulting in different profiles for each unique combination of these parameters.
Our method allows for longitudinal measurement of developmental timing of single animals.
Thus, measurement of developmental enzyme patterns is proposed as an approach that directly evaluates acquisition of metabolic competence of fundamental organ systems.
The development of appropriate biomarkers of cumulative exposure, and their measurement at developmental points where exposure is critical, are required to test the environmental estrogen hypothesis.
Recently, a noninvasive combined measurement of developmental kinetics and morphology with oxygen consumption allowed a reliable prediction of pregnancy rates from IVP bovine embryos [ 19].
A second explanation of our unexpected similarities between adolescents and adults in their antecedent structure of SEIM use refers to the statistically disadvantageous measurement of developmental status as a dichotomy.
During size measurements, the developmental stage of embryos in the brood chamber of mature adults, date, and time were recorded to refine estimates of the timing of maturity (Am) and adult instar durations, (A1, A2, A3) [ 45, 58].
However, any putative measurement error in developmental measures would be likely to obscure a signal and lead to type II error as opposed to type I error.
Therefore, organizational density is a good measurement of the developmental level and institutional environment of organizations.
The measurement of insect developmental, survival and reproductive responses to temperature poses practical challenges because of their modality, variability among individuals and high mortality near the lower and upper threshold temperatures.
