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We measured urinary concentrations of 14 phthalate metabolites and serum levels of reproductive hormones.
We measured urinary concentrations of BPA among male and female patients from the Massachusetts General Hospital Fertility Center.
To assess urinary albumin excretion, we measured urinary concentrations of albumin and Cr (albumin/Cr ratio) in an early-morning spot urine sample.
In addition, Oglobline et. al measured urinary concentrations of dialkyl metabolites in 48 adults from Australia that were not occupationally exposed to organophosphates [ 44].
Previous investigators quantified serum BPA concentrations using a commercially available enzyme-linked immunosorbent assay (ELISA) kit, whereas we measured urinary concentrations of this toxicant using the gold-standard detection technique, isotope dilution mass spectrometry [ 20].
We measured urinary concentrations of mono 2-ethylhexyl) phthalate (mono 2-ethylhexylytic metabolite of di(2-ethylhexyl) phthalate (DEHP), and other phthalate MEHPesthe metabolites, along withydrolyticvels of free thyroxine (T4), total triiodothyronine (T3), and thyroid-stimetaboliteofmone (TSH).
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We measured urinary concentration of NAG using a modified enzyme assay according to Lockwood and corrected for nonspecific conversion (HaemoScan, Groningen, the Netherlands).
The NYC HANES included a biomonitoring component to evaluate pesticide exposures by measuring urinary concentrations of organophosphate and pyrethroid metabolites.
Hadfield and colleagues [ 15] assessed total 3-OMG absorption in a critically ill cohort by measuring urinary concentrations and found it to be reduced to approximately 20% of normal [ 15].
Also, since phthalates are rapidly metabolized in the body to their respective hydrolytic monoesters and oxidized monoesters [ 1], research studies generally measure urinary concentrations of phthalate metabolites as biomarkers of exposure to phthalates.
See related research by Su et al., http://ccforum.com/content/15/5/R250 In the previous issue of Critical Care, Su and colleagues [ 1] reported on the usefulness of measuring urinary concentrations of the soluble form of the triggering receptor expressed on myeloid cells-1 (sTREM-1) during sepsis.
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