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To verify that the as-prepared ACs contained only atomically dispersed Ni/Fe atoms, X-ray absorption near-edge structure (XANES) and extended X-ray absorption fine structure (EXAFS) spectra were measured (Supplementary Fig. 10).
Specifically, mir-1246 mimic was diluted to a concentration range of 1.386×1012 1.386×106 copies per reaction and each point plotted is an average of triplicate fluorescence values for each standard concentration measured (Supplementary Fig. 3g, HCT116-derived exosomes are marked with an arrow).
To obtain a good estimate of the binding affinities between the pyrene moieties of R4·4Cl and γ-CD, a reference heterorotaxane SR4·4Cl was synthesised and the averaged binding affinity (0.9 × 104 M−1) between its pyrene moiety and γ-CD was measured (Supplementary Figs 48−55) in D2O.
The levels of important adipokines, including adiponectin and leptin, were also measured (Supplementary Figure S2).
Similar results were obtained when the LC3-II/actin ratio was measured (Supplementary Material, Fig. S1).
Finally, caspases-3/-7-like activity was measured (Supplementary Figure S7).
Similar(39)
All transition rates are retrieved from previous studies or estimated from the experimental parameters measured here (Supplementary Table 7 2,3.
Furthermore, the current voltage (I V) curve at a bias voltage from –3 to 3 V was also measured in Supplementary Fig. 7.
One hundred and sixty-seven different mRNA species involved in stemness, inflammation, immunity, self-renewal, differentiation and migration were measured (see Supplementary information).
Strong scaling values from 35 nodes were >97% for all numbers of nodes measured here (Supplementary Table S2).
The genotyping of these SNPs was extended to over 2,100 cases in which ZnT8A was measured (electronic supplementary material [ESM] Table 1).
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