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TRACP 5b is an enzyme secreted by osteoclasts and its activity can be measured specifically in serum by immunoassay[ 9].
Allelic RNA expression ratios, when measured specifically in splice variants or alternatively expressed untranslated regions, can identify genetic variants affecting RNA processing [ 12- 14].
In agreement with these data, upregulation of the MES marker CD44 was measured specifically in GBM xenografts from CBD-treated mice, in vivo.
The decrease in single-unit firing was measured specifically in somatosensory cortex, which was the only region to exhibit a negative BOLD signal (For example, motor and cingulate cortex exhibited positive responses; Figure 2A).
This approach has not been measured specifically in cases of unexplained falls, but may be justified in terms of clinical risk in cases of abrupt-onset, extremely frequent falls, with features of heart disease.
Unfortunately, renal function was not measured specifically in this study, but a recent study suggests that long-term GLP-2 treatment may have beneficial effects on renal function as evidenced by improvements in creatinine clearance.
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We have not measured specifically telomeric length in the cells, but results with immuno-FISH suggest that on average telomeres of LNCaP cells were longer than in SQ20B cells, which had fairly short telomeres prior to expression of the mutant.
Additionally, initiatives such as CORC have promoted greater awareness or the use and type of outcome measures, specifically, in the use of generic rather than condition-specific measures that allow comparisons to benchmarks which should lead to improvements in practice [ 27].
The derived mapping algorithm establishes a link between EORTC HRQoL data and the EQ-5D as a utility-based outcomes measure specifically in patients with multiple myeloma.
Thus, we think that further research is needed to explain the impact of retinopathy on these measures, specifically in type 2 diabetic patients in the absence of other associated complications.
While the previous work on the selection of items identified some items relevant for any population [ 1], this paper develops measures specifically in the context of joint replacement surgery, mainly for osteoarthritis.
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