Exact(12)
The reason for this discrepancy is unclear but one possible explanation is that the latter study measured selection pressure by measuring the frequency of variants in optimal epitopes in subjects with the presenting allele compared with subjects lacking the presenting allele arguing that a high frequency of variants in subjects without the presenting allele was evidence of a low fitness cost.
The measured selection responses and the calculated predicted genetic responses were found to be similar.
However, even when we removed all other terms from the model and measured selection differentials on swimming speed alone, the results were not significant.
A number of studies have measured selection in nature in an effort to understand how populations adapt to their environment over time [ 1, 2].
A number of studies have measured selection in nature to understand how populations adapt to their environment; however, the temporal dynamics of selection are rarely investigated.
It is important to remember that the following conclusions are merely hypotheses, in part because few studies have formally measured selection on salmon in response to environmental change.
Similar(48)
Because natural selection drives adaptive evolution, measuring selection is an integral part of evolutionary biology.
However, measuring selection is not equivalent to uncovering the biological processes responsible for generating it.
Multiple regression, coupled with visualization of the fitness function, is the primary approach used to measure selection.
Therefore, the dN/dS ratio test must be applied carefully for measuring selection pressure on M. tuberculosis genes.
Specifically, the Ka / Ks metric was designed to measure selection pressure on amino acid substitutions, assuming that the synonymous substitution rate Ks reflects the neutral nucleotide substitution rate.
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