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Biomarker data were not available prior to measured renal function.
In our study we only measured renal function changes during hospitalization and not after discharge.
Our study suggests associations of eGFRcys with frailty may have a similar magnitude of association using directly measured renal function.
Serum chemistry parameters measured (renal function, serum protein, T4, electrolyte balance, pancreas function, liver function, and lipid metabolism) were within normal ranges in both control rats and in rats exposed to PCB3.
In the Seychelles' sample, we measured renal function using the accepted gold standard, inulin clearance, and found that ABCB1 genetic variants are associated with the haemodynamic profile, i.e. GFR, ERPF and RVR in these individuals of African descent with a positive family history of hypertension.
Further work is required to confirm this association is seen with measured renal function.
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Objective: To use sequential 1-CrCl measurements to measure renal function in critically ill patients with or at risk of AKI over 72 hours and to compare this with traditional methods of assessing AKI.
The measurements performed, however, are the gold standard for measuring renal function, with a day-to-day variation coefficient of less than 3%% for GFR and 5 % for ERPF.
Therefore it would be of value to have a simple, safe test to measure renal function.
The determinations of the plasmatic creatinine and its clearance or the estimate of the glomerular filtration rate by means of equations derived from the creatinine are the methods most often used in order to measure renal function, although not without problems in pre-dialysis.
99mTc-DTPA kits are commercially available for renal imaging and are used to measure renal function and glomerular filtration rate.
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