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To address such shortcomings, we measured protein diffusivity and accumulation within PEG hydrogels with varying PEG molecular weight, concentration and crosslinking mechanism.
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Accordingly, the ACF analysis yields a quite homogeneous distribution of protein diffusivity across NE (Fig. 6B).
The hydrodynamic radius and protein diffusivity in water were estimated by eqs 2 and 3, respectively.
In our protein diffusivity experiments, it was found that hydrogels consisting of either 100% PEG PQ or 100% PEG PQ alloc) exhibit similar diffusivities for proteins ranging from 5 to 50 kDa.
At equal concentration, mixtures of IgG and albumin reduce filtrate flux and protein diffusivity more than pure solutions; this results from protein protein interactions [ 6].
Protein diffusivity depends not only on particle size (molecular weight), but also on temperature and the viscosity of the intracellular microenvironment.
Thermal conductivity was calculated from the measured thermal diffusivity, specific heat, and sheet mass density.
The thermal conductivity was evaluated from the measured thermal diffusivity and heat capacity.
The results was coincided with experiment work accompliashed by Martin et al. (2006), who measured oxygen diffusivity with mine.
The measured Sc diffusivity is consistent with the literature values.
Uptake and elution experiments were performed to quantify the transport behavior of selected proteins, specifically to estimate intraparticle protein diffusivities.
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